Will Parker has been destroyed by a local politician and now must steal to feed his family. He steals a steer from the Three Mesquiteers.
A fast-paced, enjoyable entry in the long-running Three Mesqueteers Western series, Heroes of the Saddle featured the three cowboy pals promising to look after Peggy Bell (Patsy Lee Parsons), the little daughter of mortally wounded rodeo champ Montana (Kermit Maynard). Legal technicalities, however, halt the adoption proceeding and Stony (Robert Livingston), Rusty (Raymond Hatton), and Rico (Duncan Renaldo) can only watch as the little girl is placed in the county orphanage.
In this western, the Three Mesquiteers must find a killer and his band after they murder an official from the State Agricultural Service who had come to investigate an outbreak of hoof and mouth disease. The killer is fearful that the official would quarantine his entire herd. Unfortunately for the foolish rancher, if the herd is not isolated, all of his cows and those of his neighbors will die anyway. The heroes are assisted by Buck the clever Great Dane.
The Mesquiteers return to Texas after the Civil War to find Army carpetbaggers fighting the local bushwackers. They quickly learn that Capt. Hawks and his men are the culprits and join up with Morgan and his men.
The Mesquiteers capture a horse thief who escapes justice through a crooked judge. They gather signatures urging the governor to investigate but a friend with the petition is murdered. Stony is accused.
Talbot uses a phony land grant to rule thirteen million acres, taxing everyone heavily and evicting those who won't pay. The Three Mesquiteers becomes mysterious "night riders" to fight this evil.
The Three Mesquiteers fight cattle rustlers.
The three Mesquiteers try to recover the gold stolen by a gang in its effort to ruin the banker/mayor who ordered them to leave town.